WELCOME to Solprana, Adam Jacques Third party tested for purity and potency Happy Health Core ships now. Happy Heart: reserve your bottle Evidence-Based Formulas Adam Jacques joins our team as a Subject Matter Expert. WELCOME to Solprana, Adam Jacques Third party tested for purity and potency Happy Health Core ships now. Happy Heart: reserve your bottle Evidence-Based Formulas Adam Jacques joins our team as a Subject Matter Expert.
Back to shop
Happy Heart

Happy Heart Core

A daily cardiovascular foundation supporting heart health, circulation, metabolic balance, mitochondrial energy, antioxidant systems, and B vitamin methylation pathways. Happy Heart Core complements but does not replace prescribed cardiovascular care.
$79 30 day supply
  • 30 day supply, one bottle
  • Third party tested for purity and potency
  • Vegan capsules, clean label, no CBD or THC
  • Free shipping on all US orders

Your cart

Your cart is empty. Add a formulation above to begin.

Scientific Overview
Happy Heart Core is the entry point to the Happy Heart system. It supplies the vitamins, minerals and cofactors the cardiovascular system draws on every day, so circulation, metabolic balance and cellular energy production have the raw materials they require.

Benefits

  • Supplies 200 mg of magnesium as buffered bisglycinate chelate
  • Supports normal homocysteine metabolism with folate, B12, B6, and riboflavin in active forms
  • Supports normal muscle and nerve function
  • Selenium supports the antioxidant enzyme glutathione peroxidase
  • Every dose disclosed, with no proprietary blends

How it works

  1. 01

    Magnesium is a cofactor in more than 300 enzymatic reactions, including those that regulate vascular smooth muscle tone and cardiac rhythm.

  2. 02

    Folate, vitamin B12, vitamin B6, and riboflavin are the cofactors of the methylation cycle that clears homocysteine. Core supplies folate as Quatrefolic® 5-MTHF, which does not require enzymatic activation.

  3. 03

    Selenium is required for glutathione peroxidase. Controlled trials have not shown that selenium supplementation prevents cardiovascular disease, and no such claim is made here.

Ingredients

Magnesium, 200 mg As buffered bisglycinate chelate. Enzymatic cofactor for vascular tone and cardiac rhythm
Folate, 680 mcg DFE As Quatrefolic® 5-MTHF. Methylation and homocysteine metabolism
Vitamin B12, 500 mcg As methylcobalamin. Methylation and nerve function
Vitamin B6, 10 mg As pyridoxal-5′-phosphate. Homocysteine metabolism
Riboflavin (B2), 5 mg As riboflavin-5′-phosphate. Cofactor in folate metabolism
Pantothenic acid (B5), 10 mg Precursor of coenzyme A
Selenium, 100 mcg As L-selenomethionine. Required for glutathione peroxidase
Vitamin D3, 1.25 mcg (50 IU) As cholecalciferol. A small amount, 6% of the Daily Value

Research references

  • Zhang X, et al. Effects of magnesium supplementation on blood pressure: a meta-analysis of randomized double-blind placebo-controlled trials. Hypertension. 2016;68(2):324–333.
  • Homocysteine Lowering Trialists’ Collaboration. Dose-dependent effects of folic acid on blood concentrations of homocysteine. Am J Clin Nutr. 2005;82(4):806–812.
  • Martí-Carvajal AJ, et al. Homocysteine-lowering interventions for preventing cardiovascular events. Cochrane Database Syst Rev. 2017;8:CD006612.
  • Huo Y, et al. Efficacy of folic acid therapy in primary prevention of stroke among adults with hypertension in China: the CSPPT randomized clinical trial. JAMA. 2015;313(13):1325–1335.

Reference summaries shown by topic. Full citations are published in the Research References library.

Scientific disclaimer: these statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease. Solprana formulations are designed to complement, not replace, care prescribed by a qualified healthcare provider. Consult your provider before beginning any supplement, particularly if you take prescription medication, are pregnant or are nursing.

Two free guides: Essential Vitamins and Minerals, and Bioavailability and Absorption

What each of 28 vitamins and minerals does in the body and how much adults need, plus why the dose on a label is not the dose you absorb. Enter your email to download both instantly.

What are you interested in learning more about?